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La PDE5 è la fosfodiesterasi predominante nei vasi polmonari. L’inibizione della PDE5 da parte di tadalafil aumenta le concentrazioni della cGMP determinando un rilassamento della muscolatura liscia dei vasi polmonari e una vasodilatazione del letto vascolare polmonare.

For every evitare danni all’ambiente, non gettare alcun medicinale nell’acqua di scarico e nei rifiuti domestici. Chiedere sempre al farmacista arrive eliminare i medicinali che non si utilizzano più.

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